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In nonclinical studies in mice, rats, and rabbits, mestinon for myasthenia gravis was developmentally toxic when administered to pregnant animals at doses similar to or lower than those used clinically.

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Because it’s not as often used anymore, (it was a drug du jour for a while, until the manufacturer got busted for falsely marketing if for everything) I don’t see too many people withdrawing from it, but since a lot of docs prescribe all sorts of things even after drugs are found ineffective or dangerous, it’s still prescribed and so yes, some people do need to come off of it!

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